Homoquinolinic acid

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Cat.No. 0197 - Homoquinolinic acid | C8H7NO4 | CAS No. 490-75-5
Description: Selective, potent NMDA agonist
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent NMDA receptor agonist; subtype-selective.

Technical Data

M. Wt 181.15
Formula C8H7NO4
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 490-75-5
PubChem ID 3080554
InChI Key HQPMJFFEXJELOQ-UHFFFAOYSA-N
Smiles OC(=O)CC1=CC=CN=C1C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility Soluble to 100 mM in 1eq. NaOH

Product Datasheets

Certificate of Analysis / Product Datasheet
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References

References are publications that support the biological activity of the product.

Olverman et al (1988) Structure/activity relations of NMDA receptor ligands as studied by their inhibition of [3H]-D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience 26 17 PMID: 2901691

Prado de Carvalho et al (1996) The endogenous agonist quinolinic acid and the non-endogenous homoquinolinic acid discriminate between NMDAR2 receptors subunits. Neurochem.Int. 28 445 PMID: 8740453

Stone (1984) Excitant activity of methyl derivatives of quinolinic acid on rat cortical neurones. Br.J.Pharmacol. 81 175 PMID: 6546701


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Citations for Homoquinolinic acid

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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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