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Selective partial FFA4 (GPR120) agonist. Induces ERK and [Ca2+]i responses in cells expressing GPR120, but not those expressing GPR40.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 372.5. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.68 mL||13.42 mL||26.85 mL|
|5 mM||0.54 mL||2.68 mL||5.37 mL|
|10 mM||0.27 mL||1.34 mL||2.68 mL|
|50 mM||0.05 mL||0.27 mL||0.54 mL|
References are publications that support the biological activity of the product.
Hara et al (2009) Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch.Pharmacol. 380 247 PMID: 19471906
Sun et al (2010) Structure-activity relationships of GPR120 agonists based on a docking simulation. Mol.Pharmacol. 78 804 PMID: 20685848
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Keywords: Grifolic acid, Grifolic acid supplier, G, protein-coupled, receptors, GPR120, orphan, selective, partial, agonists, FFA4, free, fatty, acid, Free, Fatty, Acid, Receptors, 4581, Tocris Bioscience
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