Selective partial FFA4 (GPR120) agonist. Induces ERK and [Ca2+]i responses in cells expressing GPR120, but not those expressing GPR40.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 372.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||2.68 mL||13.42 mL||26.85 mL|
|5 mM||0.54 mL||2.68 mL||5.37 mL|
|10 mM||0.27 mL||1.34 mL||2.68 mL|
|50 mM||0.05 mL||0.27 mL||0.54 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Hara et al (2009) Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch.Pharmacol. 380 247 PMID: 19471906
Sun et al (2010) Structure-activity relationships of GPR120 agonists based on a docking simulation. Mol.Pharmacol. 78 804 PMID: 20685848
If you know of a relevant reference for Grifolic acid, please let us know.
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Keywords: Grifolic acid, supplier, G, protein-coupled, receptors, GPR120, orphan, selective, partial, agonists, FFA4, free, fatty, acid, receptors, Free, Fatty, Acid, Receptors, Tocris Bioscience
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