GRF (ovine)

Discontinued Product

Unfortunately GRF (ovine) (Cat. No. 1187) has been withdrawn from sale for commercial reasons.
Cat.No. 1187 - GRF (ovine) | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Ile-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Asn-Arg-Gln-Gln-Gly-Glu-Arg-Asn-Gln-Glu-Gln-Gly-Ala-Lys-Val-Arg-Leu-NH2
Description: Endogenous ghrelin receptor agonist
Alternative Names: Growth Hormone-Releasing Factor (ovine)
Datasheet
Citations
Literature

Biological Activity

Hypothalamic peptide which stimulates the release of growth hormone.

Licensing Information

Sold with the permission of the SALK Institute

Technical Data

M. Wt 5123
Formula C221H368N72O66S
Sequence YADAIFTNSYRKILGQLSARKLLQDIMNRQQGERNQEQGAKVRL

(Modifications: Leu-44 = C-terminal amide)

Storage Desiccate at -20°C
Smiles [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 5123. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.2 mL 0.98 mL 1.95 mL
5 mM 0.04 mL 0.2 mL 0.39 mL
10 mM 0.02 mL 0.1 mL 0.2 mL
50 mM 0 mL 0.02 mL 0.04 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Campbell et al (1991) GRF analogs and fragments: correlation between receptor binding, activity and structure. Peptides 12 569 PMID: 1656403

Campbell and Scanes (1992) Evolution of the growth hormone-releasing factor (GRF) family of peptides. Growth Regul. 2 175 PMID: 1290954

Laburthe et al (1996) Receptors for VIP, PACAP, secretin, GRF, glucagon, GLP-1, and other members of their new family of G protein-linked receptors: structure-function relationship with special reference to the human VIP-1 receptor. Ann.N.Y.Acad.Sci. 805 94 PMID: 8993396

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Keywords: GRF (ovine), supplier, Stimulates, growth, hormone, release, GHRH, Receptors, GRF, Growth-Hormone, Releasing, Hormone, Glucagon, agonists, Growth, Hormone-Releasing, Factor, (ovine), Ghrelin, Receptors, Tocris Bioscience

Citations for GRF (ovine)

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