Pricing Availability   Qty
Description: Type II 5α-reductase inhibitor
Alternative Names: MK 906
Chemical Name: (5α,17β)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
Purity: ≥99% (HPLC)
Citations (2)

Biological Activity for Finasteride

Finasteride is an antiandrogen that inhibits type II 5α reductase (IC50 = 65 nM). Suppresses the conversion of testosterone to dihydrotestosterone. Reduces prostatic dihydrotestosterone levels and prostate size in vivo. Orally active.

Technical Data for Finasteride

M. Wt 372.54
Formula C23H36N2O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 98319-26-7
PubChem ID 57363
Smiles C[C@@]12[C@](CC[C@@H]2C(NC(C)(C)C)=O)([H])[C@]3([H])CC[C@@]4([H])NC(C=C[C@]4(C)[C@@]3([H])CC1)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for Finasteride

Solvent Max Conc. mg/mL Max Conc. mM
DMSO 37.25 100
ethanol 37.25 100

Preparing Stock Solutions for Finasteride

The following data is based on the product molecular weight 372.54. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.68 mL 13.42 mL 26.84 mL
5 mM 0.54 mL 2.68 mL 5.37 mL
10 mM 0.27 mL 1.34 mL 2.68 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets for Finasteride

Certificate of Analysis / Product Datasheet
Select another batch:

References for Finasteride

References are publications that support the biological activity of the product.

Thigpen and Russell (1992) Four-amino acid segment in steroid 5α-reductase 1 confers sensitivity to finasteride, a competitive inhibitor. J.Biol.Chem. 267 8577 PMID: 1314830

Gao et al (2004) Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5α-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia. Endocrinology 145 5420 PMID: 15308613

Mukai et al (2008) Studies on neurosteroids XXV. Influence of a 5α-reductase inhibitor, finasteride, on rat brain neurosteroid levels and metabolism. Biol.Pharm.Bull. 31 1646 PMID: 18758053

If you know of a relevant reference for Finasteride, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Other Reductase Inhibitors

Keywords: Finasteride, Finasteride supplier, Type, II, 5α-reductases, 5alpha-reductases, inhibitors, inhibits, MK906, MK, 906, Other, Reductase, Androgen, Receptor, 3293, Tocris Bioscience

2 Citations for Finasteride

Citations are publications that use Tocris products. Selected citations for Finasteride include:

Handa et al (2013) Central 5-α reduction of testost. is required for testosterone's inhibition of the hypothalamo-pituitary-adrenal axis response to restraint stress in adult male rats. Nat Neurosci 1529 74 PMID: 23880372

Ferando and Mody (2013) Altered gamma oscillations during pregnancy through loss of δ subunit-containing GABA(A) receptors on parvalbumin interneurons. Front Neural Circuits 7 144 PMID: 24062647

Do you know of a great paper that uses Finasteride from Tocris? Please let us know.

Reviews for Finasteride

There are currently no reviews for this product. Be the first to review Finasteride and earn rewards!

Have you used Finasteride?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review