Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
dTAG-Biotin is an affinity probe for mutant FKBP12F36V proteins. Comprises the ligand ortho-AP1867, selective for F36V single-point mutated FKBP12, joined by a PEG3 linker to biotin. It can be used for chemical biology studies such as proteomics, enrichment studies, dimerization experiments, and assay validation.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 1094.33. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||0.91 mL||4.57 mL||9.14 mL|
|5 mM||0.18 mL||0.91 mL||1.83 mL|
|10 mM||0.09 mL||0.46 mL||0.91 mL|
|50 mM||0.02 mL||0.09 mL||0.18 mL|
References are publications that support the biological activity of the product.
Nabet et al (2018) The dTAG system for immediate and target-specific protein degradation. Nat.Chem.Biol. 14 431 PMID: 29581585
If you know of a relevant reference for dTAG-Biotin, please let us know.
Keywords: dTAG-Biotin, dTAG-Biotin supplier, dTAG, biotin, affinity, probe, FKBP12F36V, protein, mutant, ortho-AP1867, FKBP12, F36V, TAG, Degradation, Platform, 7883, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for dTAG-Biotin. Do you know of a great paper that uses dTAG-Biotin from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review dTAG-Biotin and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
This brochure highlights the tools and services available from Bio-Techne to support Targeted Protein Degradation research, including:
Degraders (e.g. PROTACs) are bifunctional small molecules, that harness the Ubiquitin Proteasome System (UPS) to selectively degrade target proteins within cells. They consist of three covalently linked components: an E3 ubiquitin ligase ligand, a linker and a ligand for the target protein of interest. Authored in-house, this poster outlines the generation of a toolbox of building blocks for the development of Degraders. The characteristics and selection of each of these components are discussed. Presented at EFMC 2018, Ljubljana, Slovenia