DL-AP7

Discontinued Product

DL-AP7 (Cat. No. 0104) has been withdrawn from sale for commercial reasons.
Description: Selective NMDA antagonist
Chemical Name: DL-2-Amino-7-phosphonoheptanoic acid
Datasheet
Citations (2)
Reviews
Literature (11)

Biological Activity for DL-AP7

DL-AP7 is a first generation phosphono NMDA antagonist. Anticonvulsant.

Technical Data for DL-AP7

M. Wt 225.18
Formula C7H16NO5P
Storage Store at RT
CAS Number 85797-13-3
PubChem ID 3122
InChI Key MYDMWESTDPJANS-UHFFFAOYSA-N
Smiles NC(C(O)=O)CCCCCP(O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for DL-AP7

References are publications that support the biological activity of the product.

Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65 PMID: 7042024

Meldrum and Chapman (1994) Competitive NMDA antagonists as drugs. In The NMDA Receptor (2nd edition). Eds. G. L. Col 457

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Keywords: DL-AP7, DL-AP7 supplier, Selective, Specific, NMDA, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGlu, Ionotropic, 78966-69-5, 0104, Tocris Bioscience

2 Citations for DL-AP7

Citations are publications that use Tocris products. Selected citations for DL-AP7 include:

Stevens et al (2010) Light-evoked NMDA receptor-mediated currents are reduced by blocking D-serine synthesis in the salamander retina. Neuroreport 21 239 PMID: 20101193

Gustafson et al (2007) Endogenous D-serine contributes to NMDA-receptor-mediated light-evoked responses in the vertebrate retina. J Neurophysiol 98 122 PMID: 17507508


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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