DJ-V 159

Discontinued Product

DJ-V 159 (Cat. No. 6645) has been withdrawn from sale for commercial reasons.
Description: GPRC6A agonist
Chemical Name: N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide
Purity: ≥98% (HPLC)
Datasheet
Citations (1)
Reviews

Biological Activity for DJ-V 159

DJ-V 159 is a GPRC6A agonist. Activates ERK and stimulates cAMP production in GPRC6A expressing HEK-293 cells. Stimulates insulin secretion from mouse β-cells in vitro. Reduces blood glucose levels in mice in vivo.

Technical Data for DJ-V 159

M. Wt 502.37
Formula C24H12F6N4O2
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 2253744-53-3
PubChem ID 137319717
InChI Key VEVNLJLJLVESLL-UHFFFAOYSA-N
Smiles O=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)C2=CC(C(NC3=CC(C(F)(F)F)=C(C#N)C=C3)=O)=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for DJ-V 159

References are publications that support the biological activity of the product.

Pi et al (2018) Computationally identified novel agonists for GPRC6A. PLoS One 13 e0195980 PMID: 29684031

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1 Citation for DJ-V 159

Citations are publications that use Tocris products. Selected citations for DJ-V 159 include:

Sheng et al (2023) Substance P aggravates ligature-induced periodontitis in mice. Front Immunol 14 1099017 PMID: 37122730


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