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Biological Activity for DJ-V 159
DJ-V 159 is a GPRC6A agonist. Activates ERK and stimulates cAMP production in GPRC6A expressing HEK-293 cells. Stimulates insulin secretion from mouse β-cells in vitro. Reduces blood glucose levels in mice in vivo.
Technical Data for DJ-V 159
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for DJ-V 159
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||10.05||20 with gentle warming|
Preparing Stock Solutions for DJ-V 159
The following data is based on the product molecular weight 502.37. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||9.95 mL||49.76 mL||99.53 mL|
|1 mM||1.99 mL||9.95 mL||19.91 mL|
|2 mM||1 mL||4.98 mL||9.95 mL|
|10 mM||0.2 mL||1 mL||1.99 mL|
References for DJ-V 159
References are publications that support the biological activity of the product.
Pi et al (2018) Computationally identified novel agonists for GPRC6A. PLoS One 13 e0195980 PMID: 29684031
If you know of a relevant reference for DJ-V 159, please let us know.
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Keywords: DJ-V 159, DJ-V 159 supplier, DJ-V159, CPRC6A, agonists, agonism, diabetes, insulin, β, beta, cells, Orphan, 7-TM, Receptors, 6645, Tocris Bioscience
1 Citation for DJ-V 159
Citations are publications that use Tocris products. Selected citations for DJ-V 159 include:
Sheng et al (2023) Substance P aggravates ligature-induced periodontitis in mice. Front Immunol 14 1099017 PMID: 37122730
Do you know of a great paper that uses DJ-V 159 from Tocris? Please let us know.
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