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GPRC6A agonist. Activates ERK and stimulates cAMP production in GPRC6A expressing HEK-293 cells. Stimulates insulin secretion from mouse β-cells in vitro. Reduces blood glucose levels in mice in vivo.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
|DMSO||10.05||20 with gentle warming|
Preparing Stock Solutions
The following data is based on the product molecular weight 502.37. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.2 mM||9.95 mL||49.76 mL||99.53 mL|
|1 mM||1.99 mL||9.95 mL||19.91 mL|
|2 mM||1 mL||4.98 mL||9.95 mL|
|10 mM||0.2 mL||1 mL||1.99 mL|
References are publications that support the biological activity of the product.
Pi et al (2018) Computationally identified novel agonists for GPRC6A. PLoS One 13 e0195980 PMID: 29684031
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