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Description: Muscarinic antagonist, M2 > M3
Chemical Name: 5-[4-(4-Diethylaminobutyl)-1-piperidinylacetyl]-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one
Biological Activity for DIBA
Potent muscarinic antagonist, 13-fold selective for M2 over M3 receptors.
Technical Data for DIBA
| M. Wt | 462.63 |
| Storage | Store at RT |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for DIBA
Certificate of Analysis is currently unavailable on-line.
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References for DIBA
References are publications that support the biological activity of the product.
Bolognesi et al (1998) Universal template approach to drug design: polyamines as selective muscarinic receptor antagonists. J.Med.Chem. 41 4150 PMID: 9767650
Cohen et al (1993) Synthesis and structure-activity relationship of some 5-[[[(dialkylamino)alkyl]-1-piperidinyl]acetyl]-10,11-dihydro-5H-benzo[b,e][1,4]diazepin-11-ones as M2 selective antimuscarinics. J.Med.Chem. 36 162 PMID: 8421282
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Keywords: DIBA, DIBA supplier, Non-selective, Muscarinics, 0470, Tocris Bioscience
Citations for DIBA
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Currently there are no citations for DIBA.
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