DIBA

Discontinued Product

Unfortunately DIBA (Cat. No. 0470) has been withdrawn from sale for commercial reasons.
Cat.No. 0470 - DIBA
Description: Muscarinic antagonist, M2 > M3
Chemical Name: 5-[4-(4-Diethylaminobutyl)-1-piperidinylacetyl]-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent muscarinic antagonist, 13-fold selective for M2 over M3 receptors.

Technical Data

M. Wt 462.63
Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 462.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.16 mL 10.81 mL 21.62 mL
5 mM 0.43 mL 2.16 mL 4.32 mL
10 mM 0.22 mL 1.08 mL 2.16 mL
50 mM 0.04 mL 0.22 mL 0.43 mL

Molarity Calculator

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Reconstitution Calculator

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Product Datasheets

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service
Safety Datasheet

References

References are publications that support the products' biological activity.

Bolognesi et al (1998) Universal template approach to drug design: polyamines as selective muscarinic receptor antagonists. J.Med.Chem. 41 4150 PMID: 9767650

Cohen et al (1993) Synthesis and structure-activity relationship of some 5-[[[(dialkylamino)alkyl]-1-piperidinyl]acetyl]-10,11-dihydro-5H-benzo[b,e][1,4]diazepin-11-ones as M2 selective antimuscarinics. J.Med.Chem. 36 162 PMID: 8421282

View Related Products by Product Action

View all Non-selective Muscarinic Antagonists

Keywords: DIBA, supplier, Non-selective, Muscarinics, Non-selective, Muscarinics, Tocris Bioscience

Citations for DIBA

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Currently there are no citations for DIBA.

Reviews for DIBA

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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