DIBA

Discontinued Product

DIBA (Cat. No. 0470) has been withdrawn from sale for commercial reasons.
Cat.No. 0470 - DIBA
Description: Muscarinic antagonist, M2 > M3
Chemical Name: 5-[4-(4-Diethylaminobutyl)-1-piperidinylacetyl]-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one
Datasheet
Citations
Reviews
Literature

Biological Activity

Potent muscarinic antagonist, 13-fold selective for M2 over M3 receptors.

Technical Data

M. Wt 462.63
Storage Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

Certificate of Analysis is currently unavailable on-line.
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References

References are publications that support the biological activity of the product.

Bolognesi et al (1998) Universal template approach to drug design: polyamines as selective muscarinic receptor antagonists. J.Med.Chem. 41 4150 PMID: 9767650

Cohen et al (1993) Synthesis and structure-activity relationship of some 5-[[[(dialkylamino)alkyl]-1-piperidinyl]acetyl]-10,11-dihydro-5H-benzo[b,e][1,4]diazepin-11-ones as M2 selective antimuscarinics. J.Med.Chem. 36 162 PMID: 8421282

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Keywords: DIBA, DIBA supplier, Non-selective, Muscarinics, 0470, Tocris Bioscience

Citations for DIBA

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