DHBP dibromide

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Cat.No. 0839 - DHBP dibromide | C24H38Br2N2 | CAS No. 6159-05-3
Description: Ca2+ release inhibitor
Chemical Name: 1,1'-Diheptyl-4,4'-bipyridinium dibromide
Datasheet
Citations

Biological Activity

Blocks calcium release from sarcoplasmic reticulum by direct interaction with the ryanodine receptor.

Technical Data

M. Wt 514.39
Formula C24H38Br2N2
Storage Store at RT
CAS Number 6159-05-3
PubChem ID 80262
InChI Key VRXAJMCFEOESJO-UHFFFAOYSA-L
Smiles [Br-].[Br-].CCCCCCC[N+]1=CC=C(C=C1)C1=CC=[N+](CCCCCCC)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 514.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.94 mL 9.72 mL 19.44 mL
5 mM 0.39 mL 1.94 mL 3.89 mL
10 mM 0.19 mL 0.97 mL 1.94 mL
50 mM 0.04 mL 0.19 mL 0.39 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Kang et al (1994) Effects of bipyridylium compounds on calcium release from triadic vesicles isolated from rabbit skeletal muscle. Br.J.Pharmacol. 112 1216 PMID: 7952884


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