[Des-octanoyl]-Ghrelin (rat)

Pricing Availability   Qty

Save up to 40% on RUO Reagents with BIOSPRING24 (see details)

Description: Major circulating form of ghrelin; devoid of activity at GHS receptor
Alternative Names: Des-acyl ghrelin (rat)
Purity: ≥95% (HPLC)
Citations (2)
Literature (1)

Biological Activity for [Des-octanoyl]-Ghrelin (rat)

[Des-octanoyl]-Ghrelin (rat) is a non-acylated, major circulating isoform of ghrelin that does not bind to the ghrelin receptor (GHS-R1a), nor induce growth hormone release.

Technical Data for [Des-octanoyl]-Ghrelin (rat)

M. Wt 3188.63
Formula C139H231N45O41
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 307950-60-3
PubChem ID 90488789
Smiles [H]NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for [Des-octanoyl]-Ghrelin (rat)

Solubility Soluble to 1 mg/ml in water

Product Datasheets for [Des-octanoyl]-Ghrelin (rat)

Certificate of Analysis / Product Datasheet
Select another batch:

References for [Des-octanoyl]-Ghrelin (rat)

References are publications that support the biological activity of the product.

Bedendi et al (2003) Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin. Eur.J.Pharmacol. 476 87 PMID: 12969753

Thompson et al (2004) Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a GH secretagogue receptor Endocrinology 145 234 PMID: 14551228

Cassoni et al (2004) Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines. Eur.J.Endocrinol. 150 173 PMID: 14763915

If you know of a relevant reference for [Des-octanoyl]-Ghrelin (rat), please let us know.

Keywords: [des-octanoyl]-Ghrelin (rat), [des-octanoyl]-Ghrelin (rat) supplier, circulating, ghrelin, devoid, activity, GHS-R1a, Receptors, Growth, Hormone, Secretagogue, Receptor, 1a, Ghrelin, Des-acyl, (rat), 2951, Tocris Bioscience

2 Citations for [Des-octanoyl]-Ghrelin (rat)

Citations are publications that use Tocris products. Selected citations for [Des-octanoyl]-Ghrelin (rat) include:

Kemp et al (2011) Intrarenal ghrelin infusion stimulates distal nephron-dependent sodium reabsorption in normal rats. Br J Pharmacol 57 633 PMID: 21220707

Engel et al (2015) Blockade of GH secretagogue receptor 1A signaling by JMV 2959 attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition. Psychopharmacology (Berl) 232 4285 PMID: 26319159

Do you know of a great paper that uses [Des-octanoyl]-Ghrelin (rat) from Tocris? Please let us know.

Reviews for [Des-octanoyl]-Ghrelin (rat)

There are currently no reviews for this product. Be the first to review [Des-octanoyl]-Ghrelin (rat) and earn rewards!

Have you used [Des-octanoyl]-Ghrelin (rat)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Peptides Involved in Appetite Modulation Scientific Review

Peptides Involved in Appetite Modulation Scientific Review

Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.