Discontinued Product

DCQX (Cat. No. 0196) has been withdrawn from sale for commercial reasons.
Description: NMDA antagonist, acts glycine site
Chemical Name: 6,7-Dichloroquinoxaline-2,3-dione
Literature (6)

Biological Activity for DCQX

Reported as active at the glycine site of the NMDA receptor but having little action at AMPA or kainate receptors.

Technical Data for DCQX

M. Wt 231.04
Storage Store at RT
CAS Number 25983-13-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for DCQX

Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service

References for DCQX

References are publications that support the biological activity of the product.

Kleckner and Dingledine (1989) Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-MthD.-aspartate receptors. Mol.Pharmacol. 36 430 PMID: 2550776

Ogita et al (1990) 6,7-dichloroquinoxaline-2,3-dione is a competitive antagonist specific to the strychnine-insensitive [3H]glycine binding sites on the N-MthD.-aspartate receptor complex. J.Neurochem 54 699 PMID: 1967633

Yoneda and Ogita (1989) Abolition of the NMDA-mediated responses by a specific glycine antagonist, 6,7-dichloroquinoxaline-2,3-dione (DCQX). Biochem.Biophys.Res.Commun. 164 841 PMID: 2554902

View Related Products by Target

View Related Products by Product Action

View all NMDA Receptor Antagonists

Keywords: DCQX, DCQX supplier, NMDA, Receptors, 0196, Tocris Bioscience

Citations for DCQX

Citations are publications that use Tocris products.

Currently there are no citations for DCQX.

Reviews for DCQX

There are currently no reviews for this product. Be the first to review DCQX and earn rewards!

Have you used DCQX?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Huntington's Disease Research Product Guide

Huntington's Disease Research Product Guide

This product guide provides a background to Huntington's disease research and lists around 100 products for the study of:

  • Somatic Instability
  • Proteolysis and Inclusion Bodies
  • Transcriptional Dysregulation
  • Mitochondrial Dysfunction
  • Nuclear-Cytoplasmic Transport Interference
  • Excitotoxicity
  • Stem Cells
Alzheimer's Disease Poster

Alzheimer's Disease Poster

Alzheimer's disease (AD) is a debilitating and progressive neurodegenerative disease and the most common cause of dementia, affecting approximately 30% of individuals aged over 85 years. This poster summarizes the cellular and molecular mechanisms of AD.

Depression Poster

Depression Poster

Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.

Huntington's Disease Poster

Huntington's Disease Poster

Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.

Learning & Memory Poster

Learning & Memory Poster

Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.

Parkinson's Disease Poster

Parkinson's Disease Poster

Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.