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Discontinued Product
DCQX (Cat. No. 0196) has been withdrawn from sale for commercial reasons.
Description: NMDA antagonist, acts glycine site
Chemical Name: 6,7-Dichloroquinoxaline-2,3-dione
Biological Activity for DCQX
Reported as active at the glycine site of the NMDA receptor but having little action at AMPA or kainate receptors.
Technical Data for DCQX
| M. Wt | 231.04 |
| Storage | Store at RT |
| CAS Number | 25983-13-5 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for DCQX
Certificate of Analysis is currently unavailable on-line.
Please contact Customer Service
Please contact Customer Service
References for DCQX
References are publications that support the biological activity of the product.
Kleckner and Dingledine (1989) Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-MthD.-aspartate receptors. Mol.Pharmacol. 36 430 PMID: 2550776
Ogita et al (1990) 6,7-dichloroquinoxaline-2,3-dione is a competitive antagonist specific to the strychnine-insensitive [3H]glycine binding sites on the N-MthD.-aspartate receptor complex. J.Neurochem 54 699 PMID: 1967633
Yoneda and Ogita (1989) Abolition of the NMDA-mediated responses by a specific glycine antagonist, 6,7-dichloroquinoxaline-2,3-dione (DCQX). Biochem.Biophys.Res.Commun. 164 841 PMID: 2554902
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Keywords: DCQX, DCQX supplier, NMDA, Receptors, 0196, Tocris Bioscience
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