DCQX

Discontinued Product

DCQX (Cat. No. 0196) has been withdrawn from sale for commercial reasons.
Description: NMDA antagonist, acts glycine site
Chemical Name: 6,7-Dichloroquinoxaline-2,3-dione
Datasheet
Citations
Reviews
Literature (6)

Biological Activity for DCQX

Reported as active at the glycine site of the NMDA receptor but having little action at AMPA or kainate receptors.

Technical Data for DCQX

M. Wt 231.04
Storage Store at RT
CAS Number 25983-13-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for DCQX

Certificate of Analysis is currently unavailable on-line.
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References for DCQX

References are publications that support the biological activity of the product.

Kleckner and Dingledine (1989) Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-MthD.-aspartate receptors. Mol.Pharmacol. 36 430 PMID: 2550776

Ogita et al (1990) 6,7-dichloroquinoxaline-2,3-dione is a competitive antagonist specific to the strychnine-insensitive [3H]glycine binding sites on the N-MthD.-aspartate receptor complex. J.Neurochem 54 699 PMID: 1967633

Yoneda and Ogita (1989) Abolition of the NMDA-mediated responses by a specific glycine antagonist, 6,7-dichloroquinoxaline-2,3-dione (DCQX). Biochem.Biophys.Res.Commun. 164 841 PMID: 2554902

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Keywords: DCQX, DCQX supplier, NMDA, Receptors, 0196, Tocris Bioscience

Citations for DCQX

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Reviews for DCQX

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Literature in this Area

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