DAPK Substrate Peptide

Pricing Availability Delivery Time Qty
Cat.No. 1458 - DAPK Substrate Peptide | Lys-Lys-Arg-Pro-Gln-Arg-Arg-Tyr-Ser-Asn-Val-Phe | CAS No. 386769-53-5
Description: Death associated protein kinase substrate (synthetic)
Datasheet
Citations (1)
Literature

Biological Activity

Synthetic peptide substrate for death associated protein kinase (DAPK) (Km = 9 μM).

Technical Data

M. Wt 1578.82
Formula C70H115N25O17
Sequence KKRPQRRYSNVF
Storage Desiccate at -20°C
CAS Number 386769-53-5
PubChem ID 90479796
InChI Key DTEBSHTZDDUPBW-RHBFSANCSA-N
Smiles [H]N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 1 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 1578.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.63 mL 3.17 mL 6.33 mL
5 mM 0.13 mL 0.63 mL 1.27 mL
10 mM 0.06 mL 0.32 mL 0.63 mL
50 mM 0.01 mL 0.06 mL 0.13 mL

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Velentza et al (2001) A protein kinase associated with apoptosis and tumor suppression: structure, activity and discovery of peptide substrates. J.Biol.Chem. 276 38956 PMID: 11483604


If you know of a relevant reference for DAPK Substrate Peptide, please let us know.

View Related Products by Product Action

View all Death-Associated Protein Kinase Substrates

Keywords: DAPK Substrate Peptide, supplier, Death, associated, protein, kinases, DAPK, Enzyme, Substrates, Activators, DAPK, Tocris Bioscience

1 Citation for DAPK Substrate Peptide

Citations are publications that use Tocris products. Selected citations for DAPK Substrate Peptide include:

Widau et al (2010) Protein phosphatase 2A (PP2A) holoenzymes regulate death-associated protein kinase (DAPK) in ceramide-induced anoikis. PLoS One 285 13827 PMID: 20220139


Do you know of a great paper that uses DAPK Substrate Peptide from Tocris? If so please let us know.

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Literature in this Area

Kinases

Kinases Product Listing

A collection of over 400 products for kinase research, the listing includes inhibitors of:

  • Receptor Tyrosine Kinases
  • Protein Kinases A, C, D and G
  • PI-3 Kinase, Akt and mTOR
  • MAPK Signaling
  • Receptor Serine/Threonine Kinases

Pathways for DAPK Substrate Peptide

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