δ9-Tetrahydrocannabinol

Discontinued Product

Unfortunately δ9-Tetrahydrocannabinol (Cat. No. 2741) has been withdrawn from sale for commercial reasons.
Cat.No. 2741 - D9-Tetrahydrocannabinol | C21H30O2 | CAS No. 1972-08-3
Description: Cannabinoid receptor agonist; psychoactive
Alternative Names: THC
Chemical Name: (6aR,10aR)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol
Purity: ≥95% (HPLC)
Datasheet
Citations
Literature

Biological Activity

Cannabinoid receptor agonist (Ki values are 5.05 and 3.13 nM for CB1 and CB2 receptors respectively; EC50 values are 6, 0.4 and 8 nM at CB1, CB2 and GPR55 receptors respectively). Major psychoactive constituent of marijuana. Shown to inhibit lung cancer growth and metastasis in an in vivo mouse model.

Technical Data

M. Wt 314.46
Formula C21H30O2
Storage Store at RT
Purity ≥95% (HPLC)
CAS Number 1972-08-3
Smiles CCCCCC1=CC3=C([C@]2([H])C=C(C)CC[C@]([H])2C(C)(C)O3)C(O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 314.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.18 mL 15.9 mL 31.8 mL
5 mM 0.64 mL 3.18 mL 6.36 mL
10 mM 0.32 mL 1.59 mL 3.18 mL
50 mM 0.06 mL 0.32 mL 0.64 mL

Molarity Calculator

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Product Datasheets

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References

References are publications that support the products' biological activity.

Ryberg et al (2007) The orphan receptor GPR55 is a novel cannabinoid receptor. Br.J.Pharmacol. 152 1092 PMID: 17876302

Pertwee (2008) The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. Br.J.Pharmacol. 153 199 PMID: 17828291

Preet et al (2008) Δ9-tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Oncogene 27 339 PMID: 17621270

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Citations for δ9-Tetrahydrocannabinol

Citations are publications that use Tocris products.

Currently there are no citations for δ9-Tetrahydrocannabinol.

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Pathways for δ9-Tetrahydrocannabinol

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