D-Aspartic acid

Discontinued Product

D-Aspartic acid (Cat. No. 0213) has been withdrawn from sale for commercial reasons.
Description: NMDA agonist
Chemical Name: D-Aminosuccinic acid
Datasheet
Citations (1)
Reviews
Literature (6)

Biological Activity for D-Aspartic acid

D-Aspartic acid is an endogenous NMDA receptor agonist with similar activity to the L-isomer. Also a non-metabolizable substrate for EAA uptake systems. Modulates melatonin synthesis in the pineal gland.

L-isomer also available.

Technical Data for D-Aspartic acid

M. Wt 133.1
Formula C4H7NO4
Storage Store at RT
CAS Number 1783-96-6
PubChem ID 83887
InChI Key CKLJMWTZIZZHCS-UWTATZPHSA-N
Smiles N[C@@]([H])([C@](O)=O)CC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for D-Aspartic acid

References for D-Aspartic acid

References are publications that support the biological activity of the product.

Hashimoto et al (1997) Free D-aspartate and D-serine in the mammalian brain and periphery. Prog.Neurobiol. 53 325 PMID: 9247969

Ishio et al (1998) D-Aspartate modulates melatonin synthesis in rat pinealocytes. Neurosci.Lett. 249 143 PMID: 9682837

Olverman et al (1988) Structure/activity relations of NMDA receptor ligands as studied by their inhibition of 3H-D-AP5 binding in rat brain membranes. Neuroscience 26 17 PMID: 2901691

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Keywords: D-Aspartic acid, D-Aspartic acid supplier, NMDA, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Amino, Acids, 0213, Tocris Bioscience

1 Citation for D-Aspartic acid

Citations are publications that use Tocris products. Selected citations for D-Aspartic acid include:

Cai and Ford (2018) DA Cells Differentially Regulate Striatal Cholinergic Transmission across Regions through Corelease of DA and Glutamate. Cell Rep 25 3148 PMID: 30540946


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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


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