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Non-steroidal selective estrogen receptor modulator (SERM). Displays higher affinity for estrogen receptor β (ERβ) than for ERα.
|Storage||Store at +4°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 364.43. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||27.44 mL||137.2 mL||274.4 mL|
|0.5 mM||5.49 mL||27.44 mL||54.88 mL|
|1 mM||2.74 mL||13.72 mL||27.44 mL|
|5 mM||0.55 mL||2.74 mL||5.49 mL|
References are publications that support the biological activity of the product.
Kieser et al (2010) Characterization of the pharmacore properties of novel selective estrogen receptor downregulators (SERDs). J.Med.Chem. 53 3320 PMID: 20334372
Seo et al (2006) Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential PET agents for imaging estrogen receptors in breast cancer. J.Med.Chem. 49 2496 PMID: 16610793
If you know of a relevant reference for Cyclofenil, please let us know.
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Keywords: Cyclofenil, Cyclofenil supplier, Non-steroidal, selective, estrogen, receptors, modulators, SERM, ERα, ERβ, Estrogen, and, Related, Receptors, 3999, Tocris Bioscience
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