Clofibric acid

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Cat.No. 0825 - Clofibric acid | C10H11ClO3 | CAS No. 882-09-7
Description: PPAR agonist
Chemical Name: 2-(4-Chlorophenoxy)-2-methylpropanoic acid
Datasheet
Citations
Literature

Biological Activity

PPAR agonist. Antihyperlipoproteinemic.

Technical Data

M. Wt 214.65
Formula C10H11ClO3
Storage Store at RT
CAS Number 882-09-7
PubChem ID 2797
InChI Key TXCGAZHTZHNUAI-UHFFFAOYSA-N
Smiles CC(C)(OC1=CC=C(Cl)C=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 100 mM in 1eq. NaOH

Preparing Stock Solutions

The following data is based on the product molecular weight 214.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.66 mL 23.29 mL 46.59 mL
5 mM 0.93 mL 4.66 mL 9.32 mL
10 mM 0.47 mL 2.33 mL 4.66 mL
50 mM 0.09 mL 0.47 mL 0.93 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Product Datasheets

Safety Datasheet

References

References are publications that support the products' biological activity.

Bishop-Bailey (2000) Peroxisome proliferator-activated receptors in the cardiovascular system. Br.J.Pharmacol. 129 823 PMID: 10696077

Forman et al (1997) Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ. Proc.Natl.Acad.Sci.U.S.A. 94 4312 PMID: 9113986

Shepherd (1993) Mechanism of action of fibrates. Postgrad.Med.J. 69 S34 PMID: 8497455

Merck Index 12 2437 PMID:


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Citations for Clofibric acid

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Pathways for Clofibric acid

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