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CB 13

Cat. No. 2928 2 Citations Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Description: Potent dual CB1/CB2 agonist
Chemical Name: 1-Naphthalenyl[4-(pentyloxy)-1-naphthalenyl]methanone
Purity: ≥99% (HPLC)
Datasheet
Citations (2)
Reviews
Literature (1)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for CB 13

CB 13 is a potent, orally active CB1/CB2 receptor agonist with limited brain penetration (EC50 values are 6.1 and 27.9 nM for CB1 and CB2 receptors respectively). Displays antihyperalgesic activity in a rat model of neuropathic pain with no CNS side effects.

Technical Data for CB 13

M. Wt 368.47
Formula C26H24O2
Storage Store at RT
Purity ≥99% (HPLC)
CAS Number 432047-72-8
PubChem ID 9799417
InChI Key RSUMDJRTAFBISX-UHFFFAOYSA-N
Smiles O=C(C3=CC=CC4=C3C=CC=C4)C2=CC=C(OCCCCC)C1=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for CB 13

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.85 100
ethanol 18.42 50

Preparing Stock Solutions for CB 13

The following data is based on the product molecular weight 368.47. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.71 mL 13.57 mL 27.14 mL
5 mM 0.54 mL 2.71 mL 5.43 mL
10 mM 0.27 mL 1.36 mL 2.71 mL
50 mM 0.05 mL 0.27 mL 0.54 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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Keywords: CB 13, CB 13 supplier, Potent, dual, CB1/CB2, agonists, cannabinoids, Non-Selective, Receptors, CB13, cb2r, cb1r, Non-selective, Cannabinoids, 2928, Tocris Bioscience

2 Citations for CB 13

Citations are publications that use Tocris products. Selected citations for CB 13 include:

Alvarez-Fuentes et al (2012) Development and validation of an RP-HPLC method for CB13 evaluation in several PLGA nanoparticle systems. ScientificWorldJournal 2012 737526 PMID: 22792051

Godlewski et al (2010) Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects. Chem Biol 17 1256 PMID: 21095576

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Cannabinoid Receptor Ligands Scientific Review

Cannabinoid Receptor Ligands Scientific Review

Written by Roger Pertwee, this review discusses compounds which affect the activity of the endocannabinoid system, focusing particularly on ligands that are most widely used as experimental tools and denotes compounds available from Tocris.