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Biological Activity for Cannabigerol
Cannabigerol is a partial agonist of CB2 and CB1 receptors (Ki values are 337 and 440 nM respectively). Also exhibits α2-adrenoceptor agonist activity (EC50 = 0.2 nM in mouse brain membranes).
Technical Data for Cannabigerol
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Cannabigerol
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Cannabigerol
The following data is based on the product molecular weight 316.48. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.16 mL||15.8 mL||31.6 mL|
|5 mM||0.63 mL||3.16 mL||6.32 mL|
|10 mM||0.32 mL||1.58 mL||3.16 mL|
|50 mM||0.06 mL||0.32 mL||0.63 mL|
References for Cannabigerol
References are publications that support the biological activity of the product.
Gauson et al (2007) Cannabigerol behaves as a partial agonist at both CB1 and CB2 receptors. Symposium on the Cannabinoids 206
Pertwee The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. Br.J.Pharmacol. 153 199 PMID: 17828291
Cascio et al (2010) Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. Br.J.Pharmacol. 159 129 PMID: 20002104
If you know of a relevant reference for Cannabigerol, please let us know.
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Citations for Cannabigerol
Citations are publications that use Tocris products.
Currently there are no citations for Cannabigerol. Do you know of a great paper that uses Cannabigerol from Tocris? Please let us know.
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Literature in this Area
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