You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!Submit Review
Biological Activity for Brivaracetam
Brivaracetam is an antiepileptic compound that is a ligand for synaptic vesicle glycoprotein 2A (SV2A; Kd = 50 nM for human SV2A in vitro). Brivaracetam displays selectivity for SV2A at 10 μM, against a panel of 55 receptors, enzymes, ion channels and transporters. In mice, Brivaracetam protects against clonic audiogenic seizures.
Technical Data for Brivaracetam
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Brivaracetam
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions for Brivaracetam
The following data is based on the product molecular weight 212.29. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.71 mL||23.55 mL||47.11 mL|
|5 mM||0.94 mL||4.71 mL||9.42 mL|
|10 mM||0.47 mL||2.36 mL||4.71 mL|
|50 mM||0.09 mL||0.47 mL||0.94 mL|
References for Brivaracetam
References are publications that support the biological activity of the product.
Gillard et al (2011) Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: relationship to anti-convulsant properties. Eur.J.Pharmacol. 664 36 PMID: 21575627
Rogawski (2016) A new SV2A ligand for epilepsy. Cell. 167 587 PMID: 27768878
If you know of a relevant reference for Brivaracetam, please let us know.
Keywords: Brivaracetam, Brivaracetam supplier, synaptic, vesicle, glycoprotein, 2A, SV2A, ligands, antiepileptic, Exocytosis, 7271, Tocris Bioscience
Citations for Brivaracetam
Citations are publications that use Tocris products.
Currently there are no citations for Brivaracetam. Do you know of a great paper that uses Brivaracetam from Tocris? Please let us know.
Reviews for Brivaracetam
There are currently no reviews for this product. Be the first to review Brivaracetam and earn rewards!
Have you used Brivaracetam?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image