BMS 795311

Discontinued Product

BMS 795311 (Cat. No. 5762) has been withdrawn from sale for commercial reasons.
Description: Potent cholesteryl ester transfer protein (CETP) inhibitor
Chemical Name: N-[(1R)-1-[3-(Cyclopropyloxy)-4-fluorophenyl]-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide
Purity: ≥98% (HPLC)

Biological Activity for BMS 795311

BMS 795311 is a potent cholesteryl ester transfer protein (CETP) inhibitor (IC50 = 4 nM in an enzyme-based scintillation proximity assay). Inhibits cholesteryl ester transfer and increases HDL-C levels in vivo. Orally bioavailable.

Technical Data for BMS 795311

M. Wt 671.52
Formula C33H23F10NO3
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 939390-99-5
PubChem ID 23582473
Smiles FC1=CC(OC(F)(F)C(F)F)=CC([C@@](NC(C2=CC=C(F)C(C(F)(F)F)=C2)=O)(CC3=CC=CC=C3)C4=CC=C(F)C(OC5CC5)=C4)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for BMS 795311

References are publications that support the biological activity of the product.

Qiao et al (2015) Triphenylethanamine derivatives as cholesteryl ester transfer protein inhibitors: discovery of N-[(1R)-1-(3-cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamid J.Med.Chem. 58 9010 PMID: 26524347

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Citations for BMS 795311

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Currently there are no citations for BMS 795311.

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