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Somatostatin sst5 receptor agonist (Ki values are 7.3, 13.5, 31.3 and 141 nM for sst5, sst2, sst1 and sst4 receptors respectively). Stimulates gastric emptying following i.c. administration.
(Modifications: Phe-1 = D-Phe, Trp-4 = D-Trp, Thr-8 = C-terminal amide)
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Patel and Srikant (1994) Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5). Endocrinology 135 2814 PMID: 7988476
Martinez et al (2000) Intracisternal injection of somatostatin receptor 5-preferring agonists induces a vagal cholinergic stimulation of gastric emptying in rats. J.Pharmacol.Exp.Ther. 293 1099 PMID: 10869415
Nunn et al (2002) Pharmacological characterisation of the goldfish somatostatin sst5 receptor. Eur.J.Pharmacol. 436 173 PMID: 11858797
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Keywords: BIM 23052, BIM 23052 supplier, sst5, agonists, Receptors, Somatostatin, BIM23052, 2842, Tocris Bioscience
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