BCH

Pricing Availability   Qty
Cat.No. 5027 - BCH | C8H13NO2 | CAS No. 20448-79-7
Description: LAT1 inhibitor
Chemical Name: 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid
Datasheet
Citations
Reviews
Literature

Biological Activity

Inhibitor of L-type amino acid transporter LAT1. Suppresses growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines.

Technical Data

M. Wt 155.2
Formula C8H13NO2
Storage Store at RT
CAS Number 20448-79-7
PubChem ID 115288
InChI Key MPUVBVXDFRDIPT-UHFFFAOYSA-N
Smiles NC1(C(O)=O)CC2CCC1C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 15.52 100

Preparing Stock Solutions

The following data is based on the product molecular weight 155.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 6.44 mL 32.22 mL 64.43 mL
5 mM 1.29 mL 6.44 mL 12.89 mL
10 mM 0.64 mL 3.22 mL 6.44 mL
50 mM 0.13 mL 0.64 mL 1.29 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets

Certificate of Analysis / Product Datasheet
Select another batch:

References

References are publications that support the biological activity of the product.

Kim et al (2008) BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells. Biol.Pharm.Bull. 31 1096 PMID: 18520037

Lin et al (2004) L-type amino acid transporter-1 overexpression and melphalan sensitivity in Barrett's adenocarcinoma. Neoplasia 6 74 PMID: 15068672

Fraga et al (2002) L-type amino acid transporters in two intestinal epithelial cell lines function as exchangers with neutral amino acids. J.Nutr. 132 733 PMID: 11925469


If you know of a relevant reference for BCH, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Other Ion Pumps/Transporter Inhibitors

Keywords: BCH, BCH supplier, LAT1, L-type, amino, acid, transporters, inhibitors, inhibits, Other, Ion, Pumps/Transporters, 5027, Tocris Bioscience

Citations for BCH

Citations are publications that use Tocris products.

Currently there are no citations for BCH. Do you know of a great paper that uses BCH from Tocris? Please let us know.

Reviews for BCH

There are currently no reviews for this product. Be the first to review BCH and earn rewards!

Have you used BCH?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.


New Product Guide

New Product Guide (Spring/Summer 2018)

Our new product guide highlights over 200 new products added to the Tocris Bioscience range during the second half of 2017.

  • 7-TM Receptors
  • Enzymes
  • Enzyme-Linked Receptors
  • Ion Channels
  • Nuclear Receptors
  • Transporters
  • Aptamers
  • Cell Metabolism
  • Epigenetics
  • Fluorescent Imaging
  • Signal Transduction
  • Stem Cells