BAY-u 9773

Pricing Availability Delivery Time Qty
Cat.No. 3138 - BAY-u 9773 | C27H36O5S | CAS No. 154978-38-8
Description: Dual CysLT1 and CysLT2 antagonist
Chemical Name: 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoic acid

Biological Activity

Cysteinyl leukotriene receptor antagonist with equal affinity at both CysLT1 and CysLT2 receptors (pKB values are 6.8 and 6.5 respectively). Competitive antagonist of LTC4- and LTE4-induced contractions of the guinea pig trachea.

Technical Data

M. Wt 472.64
Formula C27H36O5S
Storage Store at -80°C
CAS Number 154978-38-8
PubChem ID 5311015
Smiles CCCCC\C=C/C/C=C\C=C\C=C\[C@@H](SC1=CC=C(C(O)=O)C=C1)[C@@H](O)CCCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble in ethanol (supplied pre-dissolved in Ethanol, 0.1mg/ml)

Preparing Stock Solutions

The following data is based on the product molecular weight 472.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.12 mL 10.58 mL 21.16 mL
5 mM 0.42 mL 2.12 mL 4.23 mL
10 mM 0.21 mL 1.06 mL 2.12 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Safety Datasheet


References are publications that support the products' biological activity.

Labat et al (1992) A second cysteinyl leukotriene receptor in human lung. J.Pharmacol.Exp.Ther. 263 800 PMID: 1331415

Goranne et al (1996) Cysteinyl leukotriene receptors in the human lung: what's new? TiPS 17 342 PMID: 8979767

Back (2002) Functional characteristics of cysteinyl-leukotriene receptor subtypes. Life Sci. 71 611 PMID: 12072150

If you know of a relevant reference for BAY-u 9773, please let us know.

View Related Products by Target

View Related Products by Product Action

View all Leukotriene and Related Receptor Antagonists

Keywords: BAY-u 9773, supplier, Dual, CysLT1, CysLT2, antagonists, Receptors, leukotrienes, eicosanoids, BAY-u9773, Leukotriene, and, Related, Receptors, Leukotriene, and, Related, Receptors, Tocris Bioscience

Citations for BAY-u 9773

Citations are publications that use Tocris products.

Currently there are no citations for BAY-u 9773. Do you know of a great paper that uses BAY-u 9773 from Tocris? If so please let us know.

Reviews for BAY-u 9773

There are currently no reviews for this product. Be the first to review BAY-u 9773 and earn rewards!

Have you used BAY-u 9773?

Submit a review and receive an Amazon gift card.

$10US/$10CAN/€7/£6 gift card for a review without an image

$25US/$25CAN/€18/£15 gift card for a review with an image

*Offer only valid in the USA / Canada, UK and Europe

Submit a Review

Literature in this Area


Cardiovascular Research Product Guide

A collection of over 250 products for cardiovascular research, the guide includes research tools for the study of:

  • Hypertension
  • Thrombosis and Hemostasis
  • Atherosclerosis
  • Myocardial Infarction
  • Ischemia/Reperfusion Injury
  • Arrhythmias
  • Heart Failure

GPCR Product Listing

A collection of over 450 products for G protein-coupled receptors, the listing includes research tools for the study of:

  • Rhodopsin-like Receptors
  • Secretin-like Receptors
  • Glutamate Receptors
  • Frizzled Receptors
  • GPCR Signaling

Immunology Product Listing

A collection of over 190 products for immunology research, the guide includes research tools for the study of:

  • Chemokine and Cytokine Signaling
  • Chemotaxis
  • Complement System
  • Immune Cell Signaling
  • Inflammation

Asthma Poster

Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. This poster highlights key pathways and new therapies used to treat the condition, including those currently in clinical development.


Cardiovascular Poster

Cardiovascular disease remains one of the major causes of morbidity and mortality in the Western world and therefore this therapeutic area continues to be of great interest to researchers. This poster highlights the key GPCRs regulating vascular reactivity.