Arachidonic acid (in Tocrisolve™100)

Discontinued Product

Arachidonic acid (in Tocrisolve™100) (Cat. No. 2756) has been withdrawn from sale for commercial reasons.
Description: Endogenous free fatty acid (in water-soluble emulsion)
Chemical Name: 5Z,8Z,11Z,14Z-Eicosatetraenoic acid
Citations (2)

Biological Activity for Arachidonic acid (in Tocrisolve™100)

Endogenous free fatty acid released from phospholipids by phospholipase A2, in water-soluble emulsion (for details see TocrisolveTM 100, Cat. No. 1684). Important cellular signaling mediator and precursor of eicosanoids. Metabolized by lipoxygenases, cyclooxygenases and cytochrome P450 monooxygenases.

Tocrisolve Control also available.

Technical Data for Arachidonic acid (in Tocrisolve™100)

M. Wt 304.47
Formula C20H32O2
Storage Store at +4°C
CAS Number 506-32-1
PubChem ID 444899

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets for Arachidonic acid (in Tocrisolve™100)

Certificate of Analysis / Product Datasheet
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References for Arachidonic acid (in Tocrisolve™100)

References are publications that support the biological activity of the product.

Nakanishi et al (2006) Roles of cPLA and arachidonic acid in cancer. Biochim.Biophys.Acta 1761 1335 PMID: 17052951

Levick et al (2007) Arachidonic acid metabolism as a potential mediator of cardiac fibrosis associated with inflammation. J.Immunol. 178 641 PMID: 17202322

Higuchi et al (2007) Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12-lipoxygenase activation in glioma cells. Life Sci. 80 1856 PMID: 17400255

Keywords: Arachidonic acid (in Tocrisolve 100), Arachidonic acid (in Tocrisolve 100) supplier, Endogenous, free, fatty, acid, water-soluble, emulsion, Lipid, Metabolism, Prostanoid, eicosanoid, receptors, leukotrienes, eicosanoids, prostaglandins, prostacyclins, Leukotriene, and, Related, Receptors, Other, 2756, Tocris Bioscience

2 Citations for Arachidonic acid (in Tocrisolve™100)

Citations are publications that use Tocris products. Selected citations for Arachidonic acid (in Tocrisolve™100) include:

Park et al (2016) Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nat Immunol 17 914 PMID: 27270401

Hamtiaux et al (2011) Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism. PLoS One 6 e26823 PMID: 22046372

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