Arachidonic acid (in Tocrisolve™100)

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Cat.No. 2756 - Arachidonic acid (in Tocrisolve 100) | C20H32O2 | CAS No. 506-32-1
Description: Endogenous free fatty acid (in water-soluble emulsion)
Chemical Name: 5Z,8Z,11Z,14Z-Eicosatetraenoic acid

Biological Activity

Endogenous free fatty acid released from phospholipids by phospholipase A2, in water-soluble emulsion (for details see TocrisolveTM 100, Cat. No. 1684). Important cellular signaling mediator and precursor of eicosanoids. Metabolized by lipoxygenases, cyclooxygenases and cytochrome P450 monooxygenases.

Tocrisolve Control also available.

Technical Data

M. Wt 304.47
Formula C20H32O2
Storage Store at +4°C
CAS Number 506-32-1
PubChem ID 444899

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Preparing Stock Solutions

The following data is based on the product molecular weight 304.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.28 mL 16.42 mL 32.84 mL
5 mM 0.66 mL 3.28 mL 6.57 mL
10 mM 0.33 mL 1.64 mL 3.28 mL
50 mM 0.07 mL 0.33 mL 0.66 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Nakanishi et al (2006) Roles of cPLA and arachidonic acid in cancer. Biochim.Biophys.Acta 1761 1335 PMID: 17052951

Levick et al (2007) Arachidonic acid metabolism as a potential mediator of cardiac fibrosis associated with inflammation. J.Immunol. 178 641 PMID: 17202322

Higuchi et al (2007) Arachidonic acid promotes glutamate-induced cell death associated with necrosis by 12-lipoxygenase activation in glioma cells. Life Sci. 80 1856 PMID: 17400255

If you know of a relevant reference for Arachidonic acid (in Tocrisolve™100), please let us know.

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