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Biological Activity for APcK 110
KIT inhibitor; inhibits phosphorylation of KIT, STAT3, STAT5 and Akt. Suppresses proliferation of OCI/AML3 cells (IC50 = 175 nM). Caspase-dependant apoptosis inducer.
Technical Data for APcK 110
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References for APcK 110
References are publications that support the biological activity of the product.
Faderl et al (2009) Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer Res. 69 3910 PMID: 19383925
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Keywords: APcK 110, APcK 110 supplier, APcK110, Kit, inhibitors, inhibits, Other, RTKs, 3704, Tocris Bioscience
Citations for APcK 110
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Literature in this Area
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