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Submit ReviewSynthetic peptide ([C]-AANGKSADCSVEEEPWKREK) corresponding to C-terminal amino acids 554-573 of rat precursor glutamate transporter GLT-1 (Accession No. P31596) with a cysteine added at the N-terminus of the peptide. Used as an immunogen for anti-glutamate transporter GLT-1 (Cat. No. 2063).
M. Wt | 2337.56 |
Formula | C96H153N29O35S2 |
Sequence | CAANGKSADCSVEEEPWKREK |
Storage | Desiccate at -20°C |
Smiles | [H]N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(O)=O |
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Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Keywords: Anti-glutamate transporter GLT-1 blocking peptide, Anti-glutamate transporter GLT-1 blocking peptide supplier, anti-glutamate, transporter, GLT-1, EAAT, Excitatory, Amino, Acid, Transporters, Monoamine, Neurotransmitter, immunogen, blocking, peptides, Glutamate, 2128, Tocris Bioscience
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Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.