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Submit ReviewSynthetic peptide ([C]-QLIAQDNEPEKPVADSETKM) corresponding to C-terminal amino acids 524-543 of rat precursor glutamate transporter GLAST (Accession No. P24942) with a cysteine added at the N-terminus of the peptide. Immunogen used for anti-glutamate transporter GLAST (Cat. No. 2064).
M. Wt | 2346.6 |
Formula | C97H160N26O37S2 |
Sequence | CQLIAQDNEPEKPVADSETKM |
Storage | Desiccate at -20°C |
Smiles | [H]N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
References are publications that support the biological activity of the product.
Keywords: Anti-glutamate transporter GLAST blocking peptide, Anti-glutamate transporter GLAST blocking peptide supplier, Blocking, peptides, anti-glutamate, transporter, GLAST, EAAT, Excitatory, Amino, Acid, Transporters, Monoamine, Neurotransmitter, immunogen, Glutamate, 2129, Tocris Bioscience
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Huntington's disease (HD) is a severe monogenic neurodegenerative disorder, which is characterized by the prevalent loss of GABAergic medium spiny neurons (MSN) in the striatum. This poster summarizes the effects of mutant huntingtin aggregation implicated in the pathology of HD, as well as highlighting the use of iPSCs for HD modeling.