[Ala92]-p16 (84-103)

Pricing Availability   Qty
Cat.No. 1902 - [Ala92]-p16 (84-103) | Asp-Ala-Ala-Arg-Glu-Gly-Phe-Leu-Ala-Thr-Leu-Val-Val-Leu-His-Arg-Ala-Gly-Ala-Arg | CAS No. 189064-08-2
Description: Cdk 4 inhibitor peptide; derived from p16
Datasheet
Citations
Reviews

Biological Activity for [Ala92]-p16 (84-103)

[Ala92]-p16 (84-103) is a peptide derived from the tumor suppressor protein p16; inhibits cyclin-dependent kinase-4 (cdk4)/cyclin D1 (IC50 ~ 1.5 μM) and binds to cdk6.

Technical Data for [Ala92]-p16 (84-103)

M. Wt 2123.44
Formula C93H155N31O26
Sequence DAAREGFLATLVVLHRAGAR
Storage Desiccate at -20°C
CAS Number 189064-08-2
PubChem ID 71308539
InChI Key SRSWQMWUNOIPDH-QCDQIEFZSA-N
Smiles [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for [Ala92]-p16 (84-103)

Solubility Soluble to 2 mg/ml in water

Product Datasheets for [Ala92]-p16 (84-103)

References for [Ala92]-p16 (84-103)

References are publications that support the biological activity of the product.

Fahraeus et al (1998) Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule. Oncogene 16 587 PMID: 9482104


If you know of a relevant reference for [Ala92]-p16 (84-103), please let us know.

View Related Products by Product Action

View all CDK4 Subfamily Inhibitors

Keywords: [Ala92]-p16 (84-103), [Ala92]-p16 (84-103) supplier, Cyclin-dependent, protein, kinases, inhibitors, inhibits, Cdks, Kinase, CDK4, Subfamily, 1902, Tocris Bioscience

Citations for [Ala92]-p16 (84-103)

Citations are publications that use Tocris products.

Currently there are no citations for [Ala92]-p16 (84-103). Do you know of a great paper that uses [Ala92]-p16 (84-103) from Tocris? Please let us know.

Reviews for [Ala92]-p16 (84-103)

There are currently no reviews for this product. Be the first to review [Ala92]-p16 (84-103) and earn rewards!

Have you used [Ala92]-p16 (84-103)?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review