Discontinued Product

ACPC (Cat. No. 0260) has been withdrawn from sale for commercial reasons.
Cat.No. 0260 - ACPC | CAS No. 22059-21-8
Description: Partial NMDA agonist, acts glycine site
Chemical Name: 1-Aminocyclopropanecarboxylic acid

Biological Activity

NMDA receptor agonist acting at the glycine site.

Technical Data

M. Wt 101.1
Storage Store at RT
CAS Number 22059-21-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Product Datasheets

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Safety Datasheet


References are publications that support the biological activity of the product.

Clos et al (1996) Effect of 1-aminocyclopropanecarboxylic acid on N-methyl-D-aspartate - stimulated [3H]-noradrenaline release in rat hippocampal synaptosomes. Br.J.Pharmacol. 118 90 PMID: 8799560

Hood et al (1989) 1-Aminocyclobutane-1-carboxylic acid (ACBC): a specific antagonist of the NMDA receptor coupled glycine receptor. Eur.J.Pharmacol. 161 281 PMID: 2542048

Nadler et al (1988) 1-Aminocyclopropane-1-carboxylic acid (ACPC) mimics the effects of glycine on the NMDA receptor ion channel. Eur.J.Pharmacol. 157 115 PMID: 2466672

Popik et al (1995) [3H]-1-Aminocyclopropanecarboxylic acid, a novel probe for strychnine-insensitive glycine receptors. Eur.J.Pharmacol. 291 221 PMID: 8719405

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Keywords: ACPC, ACPC supplier, NMDA, Receptors, 0260, Tocris Bioscience

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Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!

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