Discontinued ProductUnfortunately Aceclidine hydrochloride (Cat. No. 0689) has been withdrawn from sale for commercial reasons.
Cholinergic muscarinic agonist, cholinesterase inhibitor, hypotensive.
|Storage||Store at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 205.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||4.86 mL||24.31 mL||48.62 mL|
|5 mM||0.97 mL||4.86 mL||9.72 mL|
|10 mM||0.49 mL||2.43 mL||4.86 mL|
|50 mM||0.1 mL||0.49 mL||0.97 mL|
References are publications that support the products' biological activity.
Ehlert et al (1996) The interaction of the enantiomers of aceclidine with subtypes of the muscarinic receptor. J.Pharmacol.Exp.Ther. 279 1335 PMID: 8968358
Etze et al (1993) Characterization of muscarinic receptors mediating vasodilation in rat perfused kidney. Eur.J.Pharmacol. 238 343 PMID: 8405103
Ringdahl et al (1982) Muscarinic activity and receptor binding of the enantiomers of aceclidine and its methiodide. Mol.Pharmacol. 21 594 PMID: 6125875
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Keywords: Aceclidine hydrochloride, supplier, Cholinergic, muscarinic, agonist, cholinesterase, inhibitors, inhibits, hypotensive, Non-selective, Muscarinics, Non-selective, Muscarinics, Tocris Bioscience
Citations for Aceclidine hydrochloride
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Currently there are no citations for Aceclidine hydrochloride.
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Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
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Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia, affecting approximately 47 million people worldwide. Updated in 2015, this poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease, as well as classic AD drug targets.
Learning & Memory Poster
Recognition memory enables us to make judgements about whether or not we have encountered a particular stimulus before. This poster outlines the cellular mechanisms underlying recognition memory and its links to long-term depression, as well as the use of pharmacological intervention to assess the role of neurotransmitters in recognition memory.
Schizophrenia is a debilitating psychiatric disorder that affects 1% of the worldwide population. This poster describes the neurobiology of Schizophrenia, as well as highlighting the genetic and environmental factors that play a fundamental role in the etiology of the disease. The current and emerging drug targets are also discussed.