Discontinued ProductUnfortunately 5-Oxo-ETE (Cat. No. 1796) has been withdrawn from sale for commercial reasons.
Potent oxoeicosanoid (OXE) receptor agonist (EC50 = 0.33 nM). Chemoattractant for both neutrophils and eosinophils and induces transendothelial migration of eosinophils.
|Storage||Store at -80°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 318.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||3.14 mL||15.7 mL||31.4 mL|
|5 mM||0.63 mL||3.14 mL||6.28 mL|
|10 mM||0.31 mL||1.57 mL||3.14 mL|
|50 mM||0.06 mL||0.31 mL||0.63 mL|
References are publications that support the products' biological activity.
Powell et al (1994) Effects of phorbol myristate acetate on the synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human polymorphonuclear leukocytes. Biochemistry 33 3927 PMID: 8142396
Jones et al (2003) Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils. Mol.Pharmacol. 63 471 PMID: 12606753
Patel et al (2008) Structural requirements for activation of the 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor: identification of a mead acid metabolite with potent agonist activity. J.Pharmacol.Exp.Ther. 325 698 PMID: 18292294
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Keywords: 5-oxo-ETE, supplier, Oxoeicosanoid, receptor, agonists, Receptors, leukotrienes, eicosanoids, 5-KETE, Leukotriene, and, Related, Receptors, Leukotriene, and, Related, Receptors, Tocris Bioscience
Citations for 5-Oxo-ETE
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Currently there are no citations for 5-Oxo-ETE.
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