M2 proton channel blocker (IC50 = 0.92 μM). Inhibits influenza virus M2 protein (AM2).
|Storage||Desiccate at RT|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 189.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||5.27 mL||26.35 mL||52.71 mL|
|5 mM||1.05 mL||5.27 mL||10.54 mL|
|10 mM||0.53 mL||2.64 mL||5.27 mL|
|50 mM||0.11 mL||0.53 mL||1.05 mL|
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.
References are publications that support the products' biological activity.
Wang et al (2009) Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from Influenza A Virus. J.Am.Chem.Soc. 131 8066 PMID: 19469531
If you know of a relevant reference for 4,4-Pentamethylenepiperidine hydrochloride, please let us know.
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Keywords: M2 proton channels blockers influenza virus protein AM2 modulators Other Channel Modulators
Citations for 4,4-Pentamethylenepiperidine hydrochloride
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Literature in this Area
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