3',3'-cGAMP sodium salt
STING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cells in vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemic regression in Eμ-TCL1 mice.
This product is sold in units of 359μg, equivalent to 0.5μmol.
|Storage||Store at -20°C|
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
|Solvent||Max Conc. mg/mL||Max Conc. mM|
Preparing Stock Solutions
The following data is based on the product molecular weight 718.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||13.92 mL||69.6 mL||139.2 mL|
|0.5 mM||2.78 mL||13.92 mL||27.84 mL|
|1 mM||1.39 mL||6.96 mL||13.92 mL|
|5 mM||0.28 mL||1.39 mL||2.78 mL|
References are publications that support the biological activity of the product.
Tang et al (2016) Agonist-mediated activation of STING induces apoptosis in malignant B cells. Cancer Res. 76 2137 PMID: 26951929
If you know of a relevant reference for 3',3'-cGAMP sodium salt, please let us know.
View Related Products by Product Action
Keywords: 3',3'-cGAMP sodium salt, 3',3'-cGAMP sodium salt supplier, STING, agonists, malignant, B-cells, STING-Dependent, Signaling, 5946, Tocris Bioscience
Citations for 3',3'-cGAMP sodium salt
Citations are publications that use Tocris products.
Currently there are no citations for 3',3'-cGAMP sodium salt. Do you know of a great paper that uses 3',3'-cGAMP sodium salt from Tocris? Please let us know.
Reviews for 3',3'-cGAMP sodium salt
There are currently no reviews for this product. Be the first to review 3',3'-cGAMP sodium salt and earn rewards!
Have you used 3',3'-cGAMP sodium salt?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.