3',3'-cGAMP sodium salt

Pricing Availability   Qty

Save up to 40% on RUO Reagents with BIOSPRING24 (see details)

Description: STING agonist
Chemical Name: 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt
Purity: ≥98% (HPLC)
Citations (1)

Biological Activity for 3',3'-cGAMP sodium salt

3',3'-cGAMP sodium salt is a STING agonist. Reduces B cell proliferation and induces apoptosis of malignant B cells in vitro. Suppresses 5TGM1 multiple myeloma xenograft growth in immunodeficient mice, and induces leukemic regression in Eμ-TCL1 mice.

This product is sold in units of 359μg, equivalent to 0.5μmol.

Technical Data for 3',3'-cGAMP sodium salt

M. Wt 718.37
Formula C20H22N10Na2O13P2
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 2407516-83-8
PubChem ID 121513907
Smiles [H][C@@]12COP(O[C@@]3([H])[C@@H](O)[C@@H](O[C@]3([H])COP(O[C@@]1([H])[C@@H](O)[C@@H](O2)N4C=NC5=C4N=C(NC5=O)N)(O[Na])=O)N6C=NC7=C(N)N=CN=C67)(O[Na])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 3',3'-cGAMP sodium salt

Solvent Max Conc. mg/mL Max Conc. mM
water 7.18 10

Preparing Stock Solutions for 3',3'-cGAMP sodium salt

The following data is based on the product molecular weight 718.37. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.92 mL 69.6 mL 139.2 mL
0.5 mM 2.78 mL 13.92 mL 27.84 mL
1 mM 1.39 mL 6.96 mL 13.92 mL
5 mM 0.28 mL 1.39 mL 2.78 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets for 3',3'-cGAMP sodium salt

Certificate of Analysis / Product Datasheet
Select another batch:

References for 3',3'-cGAMP sodium salt

References are publications that support the biological activity of the product.

Tang et al (2016) Agonist-mediated activation of STING induces apoptosis in malignant B cells. Cancer Res. 76 2137 PMID: 26951929

If you know of a relevant reference for 3',3'-cGAMP sodium salt, please let us know.

View Related Products by Target

View Related Products by Product Action

View all STING-Dependent Signaling Agonists

Keywords: 3',3'-cGAMP sodium salt, 3',3'-cGAMP sodium salt supplier, STING, agonists, malignant, B-cells, STING-Dependent, Signaling, 5946, Tocris Bioscience

1 Citation for 3',3'-cGAMP sodium salt

Citations are publications that use Tocris products. Selected citations for 3',3'-cGAMP sodium salt include:

Ting-Xin et al (2021) Global feather orientations changed by electric current. iScience 24 102671 PMID: 34179734

Do you know of a great paper that uses 3',3'-cGAMP sodium salt from Tocris? Please let us know.

Reviews for 3',3'-cGAMP sodium salt

There are currently no reviews for this product. Be the first to review 3',3'-cGAMP sodium salt and earn rewards!

Have you used 3',3'-cGAMP sodium salt?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review