Cat. No. 5840
Biological ActivityA library of 1280 biologically active compounds from the Tocris catalog. Covers a wide range of pharmacological targets and research areas. Compounds are supplied pre-dissolved in 250 μL 10mM DMSO solutions. A smaller volume is available as Tocriscreen Plus Mini (Cat. No. 5841).
Key Format and Product Details
- 96-well racks with Matrix storage tubes & SepraSeal caps
- Compounds arranged 80 per rack with 16 racks per library
- Pre-dissolved in DMSO
- Many compounds are exclusive to Tocris
- Unique library with low overlap
- Full chemical and biological data available
- Exceptional purity
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
on-line. Please contact Customer Service
References are publications that support the products' biological activity.
Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17 195. PMID: 26253201.
Yu et al (2015) Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell 16 142. PMID: 25658371.
Edwards et al (2014) The University of New Mexico Center for Molecular Discovery. Comb.Chem.High Throughput Screen. 17 256. PMID: 24409953.
Li et al (2011) Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research 21 196. PMID: 20956998.
Beacham et al (2010) Cell-based potassium ion channel screening using the FluxORTM assay. J.Biomol.Screen. 15 44. PMID: 20208034.
Hattori et al (2010) Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA 107 3546. PMID: 20142487.
If you know of a relevant reference for Tocriscreen Plus please let us know.
Citations are publications that use Tocris products. Selected citations for Tocriscreen Plus include:
Lansu (2017) In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol 13 (5) 529. PMID: 28288109.
Do you know of a great paper that uses Tocriscreen Plus from Tocris? If so please let us know.
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Keywords: Tocriscreen Plus, supplier, 1280, biologically, active, pre-dissolved, DMSO, 250ul, 10mM, solutions, Tocriscreen, Compound, Collections, Screening, Library, Libraries, HTS, HCS, high, throughput, content, Tocris Bioscience
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