Cat. No. 5656
Chemical Name: 1-[(3-Methoxyphenyl)methyl]-N-[4-me
Biological ActivityPotent FXR antagonist (IC50 = 7.5 nM). Exhibits no detectable cytotoxicity in cell-based assays.
Licensing InformationSold under license from the Beckman Research Institute of the City of Hope.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Yu et al (2014) Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor. Bioorg.Med.Chem. 22 2919. PMID: 24775917.
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Keywords: DY 268, supplier, DY268, farnesoid, X, receptors, antagonists, antagonism, FXR, nuclear, potent, Tocris Bioscience, LXR-like Receptor Antagonist products