Cat. No. 4446
Chemical Name: 2-[Methyl(tetrahydro-1,1-dioxido-3-
Biological ActivityInhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC50 = 2.3 μM). Selectively active against colon cancer cells in a panel of 60 different cancer cell lines.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Bialkowska et al (2011) Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening. Mol.Cancer Ther. 10 2043. PMID: 21885866.
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Keywords: CID 5951923, supplier, CID5951923, krueppel, kruppel, krüppel-like, factors, klf5, inhibitors, inhibits, Tocris Bioscience, Other Transcription Factor products