Cat. No. 4446
Chemical Name: 2-[Methyl(tetrahydro-1,1-dioxido-3-
Biological ActivityInhibitor of Krüppel-like factor 5 (KLF5) transcription factor (IC50 = 2.3 μM). Selectively active against colon cancer cells in a panel of 60 different cancer cell lines.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Bialkowska et al (2011) Identification of small-molecule inhibitors of the colorectal cancer oncogene Krüppel-like factor 5 expression by ultrahigh-throughput screening. Mol.Cancer Ther. 10 2043. PMID: 21885866.
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Keywords: CID 5951923, supplier, CID5951923, krueppel, kruppel, krüppel-like, factors, klf5, inhibitors, inhibits, Tocris Bioscience, Other Transcription Factor products