Cat. No. 3813
Chemical Name: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-6,9a,
Biological ActivityPotent selective androgen receptor modulator (SARM) (IC50 = 30 nM). Steroidal compound. Exhibits limited effects on reproductive tissues and sebaceous glands; does not repress AP-1-sensitive MMP-1 reporter. Inhibits 5α-reductase type I and II (IC50 values are 2 and 3 nM respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Schmidt et al (2009) Identification of anabolic selective androgen receptor modulators with reduced activities in reproductive tissues and sebaceous glands. J.Biol.Chem. 284 36367. PMID: 19846549.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses TFM-4AS-1 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: TFM-4AS-1, supplier, selective, androgen, receptor, modulator, AR, ligand, SARM, androgen, receptors, Tocris Bioscience, Androgen Receptor Modulator products
Find multiple products by catalog number
New Products in this Area
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.