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说明： Substrate-competitive inhibitor of GSK-3
生物活性 for L803
Novel phosphopeptide derived from GSK-3 recognition motif that acts as a substrate-competitive inhibitor of GSK-3β (IC50 = 150 μM). Displays minimal inhibition of Cdc2, MAPK, PKA, CK2, PKCδ and PKB at 200 μM.
许可信息
Sold under licence from Tel Aviv University Future Technology LP
技术数据 for L803
| 分子量 | 1198.23 |
| 公式 | C50H80N13O19P |
| 序列 |
KEAPPAPPQSP (Modifications: Ser-10 = pSer) |
| 储存 | Desiccate at -20°C |
| CAS Number | 348089-28-1 |
| PubChem ID | 10328948 |
| InChI Key | YDKNRHVNWGPNSH-ICYBEGSVSA-N |
| Smiles | [H]N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](COP(O)(O)=O)C(=O)N1CCC[C@H]1C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for L803
参考文献 for L803
参考文献是支持产品生物活性的出版物。
Plotkin et al (2003) Ins mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3. J.Pharmacol.Exp.Ther. 305 974 PMID: 12626660
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关键词: L803, L803 supplier, Substrate-competitive, inhibitors, inhibits, GSK-3, Glycogen, Synthase, Kinases, 3, Carbohydrate, Metabolism, Kinase, 2235, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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Written by Rebecca Quelch and Stefan Przyborski from Durham University (UK), this poster describes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and the generation and potential uses of organoids.
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