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Submit ReviewThreo-methylphenidate hydrochloride
说明： Inhibitor of dopamine and noradrenalin transporters. Psychomotor stimulant
别名： Ritalin
化学名： Threo-methyl α-Phenyl-2-piperidineacetate hydrochloride
纯度： ≥99% (HPLC)
生物活性 for Threo-methylphenidate hydrochloride
Threo-methylphenidate hydrochloride is a psychomotor stimulant. Inhibitor of dopamine and noradrenalin transporters that increases the extracellular concentration of dopamine and noradrenalin. Increases locomotor activity in vivo.
技术数据 for Threo-methylphenidate hydrochloride
| 分子量 | 269.77 |
| 公式 | C14H19NO2.HCl |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 298-59-9 |
| PubChem ID | 45259401 |
| InChI Key | JUMYIBMBTDDLNG-QNTKWALQSA-N |
| Smiles | [H][C@]1([C@H]([C@]2=CC=CC=C2)C(OC)=O)NCCCC1.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Threo-methylphenidate hydrochloride
参考文献 for Threo-methylphenidate hydrochloride
参考文献是支持产品生物活性的出版物。
Askenasy et al (2007) Methylphenidate (Ritalin): behavioral studies in the rat. Int.J.Neurosci. 117 757 PMID: 17454243
Leonard et al (2004) Methylphenidate: a review of its neuropharmacological, neuropsychological and adverse clinical effects. Human Psychopharm. 19 151
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关键词: Threo-methylphenidate hydrochloride, Threo-methylphenidate hydrochloride supplier, inhibitors, inhibits, dopamine, DAT, noradrenalin, noradrenaline, NET, adrenalin, transporters, Psychomotor, stimulants, neurotransmitter, Ritalin, Dopamine, Transporters, Adrenergic, 1812, Tocris Bioscience
3 篇 Threo-methylphenidate hydrochloride 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Threo-methylphenidate hydrochloride 的部分引用包括：
Beerepoot et al (2016) Pharmacological Chaperones of the DA Transporter Rescue DA Transporter Deficiency Syndrome Mutations in Heterologous Cells. J Biol Chem 291 22053 PMID: 27555326
Poulin et al (2014) Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics. Mol Pharmacol 86 378 PMID: 25028482
Parker et al (2014) Atomoxetine reduces anticipatory responding in a 5-choice serial reaction time task for adult zebrafish. PLoS One 231 2671 PMID: 24481568
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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Written by Phillip Strange and revised by Kim Neve in 2013, this review summarizes the history of the dopamine receptors and provides an overview of individual receptor subtype properties, their distribution and identifies ligands which act at each receptor subtype. Compounds available from Tocris are listed.
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