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Submit ReviewMidazolam hydrochloride
说明： Benzodiazepine agonist
别名： Dormicum,Ro 21-3981/001
化学名： 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine hydrochloride
纯度： ≥99% (HPLC)
生物活性 for Midazolam hydrochloride
Midazolam hydrochloride is a sedative/hypnotic agent that acts at the GABAA receptor benzodiazepine modulatory site.
技术数据 for Midazolam hydrochloride
| 分子量 | 362.23 |
| 公式 | C18H13ClFN3.HCl |
| 储存 | Desiccate at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 59467-96-8 |
| PubChem ID | 43032 |
| InChI Key | PLYSCVSCYOQVRP-UHFFFAOYSA-N |
| Smiles | FC(C=CC=C4)=C4C3=NCC1=CN=C(C)N1C2=CC=C(Cl)C=C23.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Midazolam hydrochloride
参考文献 for Midazolam hydrochloride
参考文献是支持产品生物活性的出版物。
Kanto (1985) Midazolam: the first water-soluble benzodiazepine. Pharmacology, pharmacokinetics and efficacy in insomnia and anesthesia. Pharmacotherapy 5 138 PMID: 3161005
Olkkola and Ahonen (2008) Midazolam and other benzodiazepines. Handb.Exp.Pharmacol. 182 335 PMID: 18175099
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关键词: Midazolam hydrochloride, Midazolam hydrochloride supplier, Benzodiazepine, agonists, GABAA, Receptors, Ro213981001, Dormicum, Ro, 21-3981/001, 2832, Tocris Bioscience
Midazolam hydrochloride 的评论
平均评分: 4 (Based on 1 Review.)
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Midazolam potentiates response of GABA-A receptors even in low concentration.
By
Anonymous on 08/17/2019
分析类型： In Vitro
种属： Rat
细胞系/组织： Cerebellum
Midazolam was used to test a response of GABA-A receptors in cerebellar granule cells; the compound has shown a clear potentiatory effect. Figure: evoked EPSCs under control (black) and with 10 microM of Midazolam in perfusion solution (white).
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*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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