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Submit ReviewLY 307452
Discontinued Product
1474 has been discontinued.
View all Glutamate (Metabotropic) Group II Receptors products.
说明： Selective group II mGlu antagonist
化学名： (4S)-4-(4,4-Diphenylbutyl)-L-glutamic acid
生物活性 for LY 307452
Selective and competitive group II metabotropic glutamate receptor antagonist. Centrally active following systemic administration in vivo.
许可信息
Sold with the permission of Eli Lilly and Company.
技术数据 for LY 307452
| 分子量 | 355.43 |
| 储存 | Desiccate at +4°C |
| CAS Number | 174393-13-6 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for LY 307452
分析证书目前不在网上提供。
请联系客户服务
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参考文献 for LY 307452
参考文献是支持产品生物活性的出版物。
Li et al (1999) Type I and II metabotropic glutamate receptor agonists and antagonists evoke cardiovascular effects after intrathecal administration in conscious rats. Br.J.Pharmacol. 128 823 PMID: 10516668
Schoepp et al (1997) LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptors. Neuropharmacology 36 1 PMID: 9144636
Wermuth et al (1996) (2S,4S)-2-amino-4-(4,4-diphenylbut-1-yl)-pentane-1,5-dioic acid: a potent and selective antagonist for metabotropic glutamate receptors negatively linked to adenylate cyclase. J.Med.Chem. 39 814 PMID: 8632404
关键词: LY 307452, LY 307452 supplier, Glutamate, (Metabotropic), Group, II, Receptors, 1474, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
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