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Submit ReviewIschemin sodium salt
说明： CBP inhibitor; cell permeable
化学名： 5-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid sodium salt
纯度： ≥99% (HPLC)
生物活性 for Ischemin sodium salt
Ischemin sodium salt is a CBP bromodomain inhibitor. Inhibits p53 interaction with CBP and decreases p53 transcriptional activity. Protects against Doxorubicin-induced apoptosis in cardiomyocytes in vitro. Cell permeable.
技术数据 for Ischemin sodium salt
| 分子量 | 357.36 |
| 公式 | C15H16N3O4SNa |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| PubChem ID | 64983 |
| InChI Key | XWNMORIHKRROGW-UHFFFAOYSA-N |
| Smiles | CC1=CC(/N=N/C2=C(C)C=C(C)C(S(=O)(O[Na])=O)=C2)=C(N)C=C1O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Ischemin sodium salt
参考文献 for Ischemin sodium salt
参考文献是支持产品生物活性的出版物。
Borah et al (2011) A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem.Biol. 18 531 PMID: 21513889
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关键词: Ischemin sodium salt, Ischemin sodium salt supplier, CBP, bromodomain, inhibitors, inhibits, p53, interaction, cell, permeable, 1357059, 00, 7, Bromodomains, 4695, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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