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Submit ReviewFlunitrazepam
说明： Acts at the benzodiazepene modulatory site
化学名： 5-(2-Fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
纯度： ≥99% (HPLC)
生物活性 for Flunitrazepam
Ligand at the GABAA receptor benzodiazepine modulatory site. Exhibits hypnotic effects; also displays anxiolytic and sedative properties.
技术数据 for Flunitrazepam
| 分子量 | 313.28 |
| 公式 | C16H12FN3O3 |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 1622-62-4 |
| PubChem ID | 3380 |
| InChI Key | PPTYJKAXVCCBDU-UHFFFAOYSA-N |
| Smiles | CN(C1=CC=C([N+]([O-])=O)C=C1C(C3=CC=CC=C3F)=NC2)C2=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Flunitrazepam
参考文献 for Flunitrazepam
参考文献是支持产品生物活性的出版物。
Johnston et al (1998) Flunitrazepam rapidly reduces GABAA receptor subunit protein expression via a protein kinase C-dependent mechanism. Br.J.Pharmacol. 124 1338 PMID: 9723942
Merck Index 14 4146
Malanciuc et al (2009) Analytical characterization of flunitra. Farmacia 57 167
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关键词: Flunitrazepam, Flunitrazepam supplier, hypnotic, benzodiazepine, gabaa, receptors, modulatory, binding, sites, agonists, GABAA, Receptors, 4047, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.
Addiction Poster
The key feature of drug addiction is the inability to stop using a drug despite clear evidence of harm. This poster describes the brain circuits associated with addiction, and provides an overview of the main classes of addictive drugs and the neurotransmitter systems that they target.