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Diazepam binding inhibitory fragment

Cat. No. 1888 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Peripheral benzodiazepine receptor agonist
别名： DBI (51-70) (human),Eikosaneuropeptide,ENP
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生物活性 for Diazepam binding inhibitory fragment

Peptide fragment corresponding to residues 51-70 of the human diazepam binding inhibitor protein; peripheral benzodiazepine receptor agonist. Induces intracellular Ca2+ increase and phagocytosis in human neutrophils, mainly through a non-peripheral benzodiazepine receptor-mediated mechanism. Also reduces ammonia-induced swelling in cultured astrocytes.

技术数据 for Diazepam binding inhibitory fragment

分子量 2150.39
公式 C91H148N26O32S
储存 Desiccate at -20°C
CAS Number 104360-70-5

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参考文献 for Diazepam binding inhibitory fragment

参考文献是支持产品生物活性的出版物。

Bender and Norenberg (1998) Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes. J.Neurosci.Res. 54 673 PMID: 9843158

Cosentino et al (2000) D.pam-binding inhibitor-derived peptides induce intracellular calcium changes and modulate human neutrophil function. J.Leukoc.Biol. 67 637 PMID: 10811003

Gray et al (1986) Cloning and expression of cDNA for human D.pam binding inhibitor, a natural ligand of an allosteric regulatory site of the γ-aminobutyric acid type A receptor. Proc.Natl.Acad.Sci.U.S.A. 83 7547 PMID: 3020548

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