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Submit ReviewBromoCatch™ Ligand, Alkyne 最新
说明： Clickable alkyne-functionalized covalent probe for BromoCatch-tagged proteins
化学名： (2R)-2-((6S)-4-(4-Acrylamidophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)butanamide
纯度： ≥95% (HPLC)
生物活性 for BromoCatch™ Ligand, Alkyne
BromoCatch™ Ligand, Alkyne is a covalent ligand engineered to irreversibly bind BromoCatch-tagged proteins via selective reaction with the E438C cysteine mutant of the Brd4-BD2 domain. Featuring a terminal alkyne appended to the BromoCatch Ligand scaffold, this ligand enables downstream modification through copper-catalyzed azide-alkyne cycloaddition (CuAAC). BromoCatch™ Ligand, Alkyne facilitates modular tagging of BromoCatch fusions with fluorophores, biotin, affinity tags, or functional moieties, offering a flexible platform for custom probe development. It enables site-specific protein labeling in vitro and is ideal for applications in chemical biology, proteomics, and multiplexed detection assays.
Please refer to this protocol for further information on how to use this product.
BromoCatch™ is a trademark of Bio-Techne Corp.
许可信息
Sold under exclusive licence from the University of Dundee
技术数据 for BromoCatch™ Ligand, Alkyne
| 分子量 | 632.78 |
| 公式 | C33H40N6O5S |
| 储存 | Store at -20°C |
| 纯度 | ≥95% (HPLC) |
| InChI Key | OFMNYRGCADESPS-VIZCGCQYSA-N |
| Smiles | CC1=C(C)SC2=C1C(C3=CC=C(C=C3)NC(C=C)=O)=N[C@@H]([C@H](C(NCCOCCOCCOCC#C)=O)CC)C4=NN=C(C)N24 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for BromoCatch™ Ligand, Alkyne
参考文献 for BromoCatch™ Ligand, Alkyne
参考文献是支持产品生物活性的出版物。
Rodriguez-Rios (2025) BromoCatch: a self-labelling tag platform for protein analysis and live cell imaging. biorxiv
If you know of a relevant reference for BromoCatch™ Ligand, Alkyne, please let us know.
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关键词: BromoCatch™ Ligand, Alkyne, BromoCatch™ Ligand, Alkyne supplier, BromoCatch, Ligand, Alkyne, covalent, ligand, Brd4-BD2, domain, CuAAC, fluorophores, biotin, affinity, tags, protein, labeling, proteomics, multiplexed, detection, assays, Platform, 8940, Tocris Bioscience
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