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BromoCatch™ Control Ligand

Cat. No. 7300 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Control ligand for use with BromoCatch™, a Self-Labeling Proteins (SLPs) tag platform
化学名： Methyl (R)-2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoate
纯度： ≥97% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for BromoCatch™ Control Ligand

BromoCatch™ Control Ligand is a control ligand for use with BromoCatch™, a Self-Labeling Proteins (SLPs) tag platform. It is a non-covalent ligand that competes for BromoCatch™ probe binding site.

Please refer to this protocol for further information on how to use this product.

BromoCatch is a trademark of Bio-Techne Corp.

技术数据 for BromoCatch™ Control Ligand

分子量 442.96
公式 C22H23ClN4O2S
储存 Store at -20°C
纯度 ≥97% (HPLC)
CAS Number 2421153-75-3
PubChem ID 146037626
InChI Key WLKVOOMXHSBIOW-APWZRJJASA-N
Smiles CC1=C(C)C(C(C2=CC=C(C=C2)Cl)=N[C@@H]([C@H](C(OC)=O)CC)C3=NN=C(C)N43)=C4S1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for BromoCatch™ Control Ligand

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 44.3 100
ethanol 44.3 100

制备储备液 for BromoCatch™ Control Ligand

以下数据基于产品分子量 442.96。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.26 mL 11.29 mL 22.58 mL
5 mM 0.45 mL 2.26 mL 4.52 mL
10 mM 0.23 mL 1.13 mL 2.26 mL
50 mM 0.05 mL 0.23 mL 0.45 mL

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产品说明书 for BromoCatch™ Control Ligand

分析证书/产品说明书
化学品安全技术说明书

参考文献 for BromoCatch™ Control Ligand

参考文献是支持产品生物活性的出版物。

Runcie et al (2018) Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem.Sci. 9 2452 PMID: 29732121

Baud et al (2014) A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes. Science 346 638 PMID: 25323695

Rodriguez-Rios et al (2025) BromoCatch: a self-labelling tag platform for protein analysis and live cell imaging. www.biorxiv.org/content/10.1101/2025.04.07.647551v1

If you know of a relevant reference for BromoCatch™ Control Ligand, please let us know.

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关键词: BromoCatch™ Control Ligand, BromoCatch™ Control Ligand supplier, BromoCatch, control, ligand, probe, non, covalent, probes, self-labeling, tags, Platform, Self-labeling, Tags, 7300, Tocris Bioscience

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