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Submit Review6655 has been discontinued.
View all Biochemicals and Molecular Biology products.Amifostine is a cytoprotectant against chemotherapy and radiotherapy. Reduces mitochondrial pyruvate use in hepatocytes but not hepatoma cells in vitro. Also inhibits angiogenesis.
Active metabolite is also available, WR 1065 (Cat. No. 3356)
| 分子量 | 214.22 |
| 公式 | C5H15N2O3PS |
| 储存 | Store at +4°C |
| CAS Number | 20537-88-6 |
| PubChem ID | 2141 |
| InChI Key | JKOQGQFVAUAYPM-UHFFFAOYSA-N |
| Smiles | NCCCNCCSP(O)(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Giannopoulou et al (2003) AmiF. inhibits angiogenesis in vivo. J.Pharmacol.Exp.Ther. 304 729 PMID: 12538828
Koukourakis et al (2016) Normal tissue radioprotection by AmiF. via Warburg-type effects. Sci.Rep. 6 PMID: 27507219
关键词: Amifostine, Amifostine supplier, amifostine, cytoprotectant, WR, 2721, protects, radiotherapy, chemotherapy, 112901-68-5, Biochemicals, and, Molecular, Biology, 6655, Tocris Bioscience
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