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Submit ReviewPotent agonist for the nociceptin/orphanin FQ receptor, NOP (ORL1). Displays approximately 100-fold higher potency than N/OFQ and produces longer lasting effects on nociception and locomotor activity in mice. Induces a significant decrease in voluntary ethanol intake in msP rats.
分子量 | 1940.21 |
公式 | C83H139N32O21F |
储存 | Desiccate at -20°C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Economidou et al (2006) Effect of novel nociceptin/orphanin FQ-NOP receptor ligands on ethanol drinking in alcohol-preferring msP rats. Peptides 27 3299 PMID: 17097763
Rizzi et al (2006) UFP-112, a novel potent and selective peptide agonist for nociceptin/orphanin FQ receptors: in vitro and in vivo studies. Soc.Neurosci.Abstr. 789 16
关键词: UFP 112, UFP 112 supplier, nociceptin, orphanin, FQ, receptor, NOP, ORL1, agonist, Receptors, 2526, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.