SMCy 5.5

Pricing Availability   Qty
Cat.No. 7295 - SMCy 5.5 | C41H46BF2N3O4 | CAS No. 2417507-09-4
说明: Fluorogenic fluorescent probe for imaging lipid droplets; suitable for use with two-photon microscopy
化学名: 6,8-Dicyclohexyl-4-((1E,3E,5E)-5-(1,1-dimethyl-3-(pent-4-yn-1-yl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-2,2-difluoro-2,8-dihydro-5H-1λ3,2λ4-[1,3,2]dioxaborinino[6,5-d]pyrimidine-5,7(6H)-dione
纯度: ≥95% (HPLC)
文献 (1)

生物活性 for SMCy 5.5

SMCy 5.5 is a fluorogenic fluorescent probe for imaging lipid droplets that exhibits sharp excitation and emission bands and high brightness. SMCy 5.5 is suitable for use with two-photon microscopy. It is useful for deep tissue imaging and 3D imaging. Excitation/emission maxima for SMCy 5.5 in THF are 643/672 nm; Quantum yield = 0.75; Extinction coefficient = 209,000 M-1 cm-1. SMCy 5.5 displays high two-photon absoprtion (TPA) cross-section values (13330 GM and 10400 GM at 770 and 820 nm, respectively). The probe also has a click reactive handle.

Optical Data for SMCy 5.5

SMCy 5.5 Dye Spectra
λabs 636 nm
λem 660 nm
Extinction Coefficient (ε) 194,000 M-1cm-1
Quantum Yield (φ) 1
Closest Laser line 640 nm
Reactive Group Alkyne
Reactivity Click
Cell Permeable Yes

技术数据 for SMCy 5.5

分子量 693.64
公式 C41H46BF2N3O4
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 2417507-09-4
Smiles CC1(/C(N(C2=C1C3=CC=CC=C3C=C2)CCCC#C)=C\C=C\C=C\C4=C(C(N(C(N5C6CCCCC6)=O)C7CCCCC7)=O)C5=[O+][B-](F)(F)O4)C


Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for SMCy 5.5

溶剂 最高浓度 mg/mL 最高浓度 mM
DMSO 6.94 10

制备储备液 for SMCy 5.5

以下数据基于产品分子量 693.64。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.1 mM 14.42 mL 72.08 mL 144.17 mL
0.5 mM 2.88 mL 14.42 mL 28.83 mL
1 mM 1.44 mL 7.21 mL 14.42 mL
5 mM 0.29 mL 1.44 mL 2.88 mL

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参考文献 for SMCy 5.5


Collot et al (2018) Ultrabright and fluorogenic probes for multicolor imaging and tracking of lipid droplets in cells and tissues. J.Am.Chem.Soc. 140 5401 PMID: 29446627

Fam et al (2018) Recent advances in fluorescent probes for lipid droplets. Materials (Basel) 11 1768 PMID: 30231571

If you know of a relevant reference for SMCy 5.5, please let us know.

关键词: SMCy 5.5, SMCy 5.5 supplier, Fluorescent, fluorogenic, probe, imaging, lipid, droplets, two-photon, microscopy, 2-photon, Lipid, Probes, and, Cell, Membrane, Stains, 7295, Tocris Bioscience

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