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Submit ReviewMorphine hydrochloride
说明： Narcotic opioid analgesic
化学名： 7,8-Didehydro-4,5-epoxy-17-methyl-(5α,6α)-morphinan-3,6-diol hydrochloride
纯度： ≥99% (HPLC)
生物活性 for Morphine hydrochloride
Morphine hydrochloride is a narcotic opioid analgesic.
技术数据 for Morphine hydrochloride
| 分子量 | 321.8 |
| 公式 | C17H19NO3.HCl |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 52-26-6 |
| PubChem ID | 5464110 |
| InChI Key | XCKKIKBIPZJUET-VYKNHSEDSA-N |
| Smiles | O[C@@H]3[C@H]5[C@]24C1=C(O5)C(O)=CC=C1C[C@@H](N(C)CC4)[C@@]([H])2C=C3.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Morphine hydrochloride
参考文献 for Morphine hydrochloride
参考文献是支持产品生物活性的出版物。
Merck Index 12 1074
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关键词: Morphine hydrochloride, Morphine hydrochloride supplier, opioid, receptors, analgesic, Miscellaneous/Non-selective, Opioids, 5158, Tocris Bioscience
4 篇 Morphine hydrochloride 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Morphine hydrochloride 的部分引用包括：
Prather et al (2013) CB1 and CB2 receptors are novel molecular targets for tamox. and 4OH-Tamoxifen. Biochem Biophys Res Commun 441 339 PMID: 24148245
Rajasekaran et al (2013) Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors. Toxicol Appl Pharmacol 269 100 PMID: 23537664
Mohammad et al (2021) Effects of intrathecal and intracerebroventricular microinjection of kaempferol on pain: possible mechanisms of action. Res Pharm Sci 16 203-216 PMID: 34084207
Jose A et al (2021) An endogenous opioid circuit determines state-dependent reward consumption. Nature 598 646-651 PMID: 34646022
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平均评分: 5 (Based on 1 Review.)
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Morphine inhibits AITC-induced p42/44 phosphorylation in brain.
By
Christopher Trummer on 10/15/2018
分析类型： In Vivo
种属： Mouse
细胞系/组织： Brain
Saline or morphine (10 mg/kg, s.c.) was injected 1 h prior to intrarectal instillation of peanut oil (Veh) or AITC 2% (v/v) in mice. Phosphorylation of p42/44 was analysed in spinal cord (Sc), thalamus (Th), hypothalamus (Hth), amygdala (Amy), and prefrontal cortex (Pfc) lysates using Western blot. Morphine significantly inhibited AITC-induced pp42/44 expression (shown in Image).
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